A Review of Recent Advances in Cell and Gene Therapy for HIV

Researchers of a review worked to summarize notable advances in cell and gene therapy for HIV disease. Since there has been evidence for modulating disease, researchers note that cell and gene therapy in the HIV space has seen significant innovation. Clinical trials are underway that hold promise for achieving durable HIV suppression. In this review, researchers review progressing areas of this subject matter including the guidance of in vivo expression of protective antibodies or antiviral proteins, the use of B cell engineering in controlling insufficient humoral immune responses to HIV, as well as T cell engineering utilizing viral vector medication of HIV-specific T cells.

Reference:
Pauza CD, Huang K, Bordon J. Advances in cell and gene therapy for HIV disease: it is good to be specific. Curr Opin HIV AIDS. 2021;16(2):83-87. doi:10.1097/COH.0000000000000666

Read More