A Review of Recent Advances in Cell and Gene Therapy for HIV
Researchers of a review worked to summarize notable advances in cell and gene therapy for HIV disease. Since there has been evidence for modulating disease, researchers note that cell and gene therapy in the HIV space has seen significant innovation.
Assessing COVID-19 Vaccinations in Those With HIV
Researchers of a study sought to examine seroconversion rates and antibody titers after two-dose COVID-19 vaccination in those with HIV with impaired CD4+ T-cell counts
Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Participants With Preexisting Primary Integrase Inhibitor Resistance
Researchers examined virologic outcomes throughout 48 weeks of treatment with of bictegravir / emtricitabine / tenofovir alafenamide (B/F/TAF) in patients who have preexisting primary integrase strand transfer inhibitor resistance (INSTI-R).
Georgia Hospital Possibly Exposes Veterans to HIV, HCV
Due to improperly sterilized equipment, over 4,600 veterans who had been given care at the Carl Vinson Veterans Affairs Medical Center in Dublin, Georgia, were tested for exposure to HIV, hepatitis B, and hepatitis C.
Preexposure Prophylaxis and Newly Diagnosed HIV
A recent study looked to examine the proportion of individuals who reported recent exposure to preexposure prophylaxis (PrEP) at HIV diagnosis over time, and data was looked at for probable reasons for failure of PrEP, baseline genotypic resistance, and clinical management using Mann-Whitney U test and Fisher’s exact test.
Study Looks at Provider Experience and Life Stressors as Impacts to Patient Adherence in HIV
According to new research that was published in AIDS and Behavior in January 2022, having an understanding of patient experiences and expectations in addition to individual life stressors in the clinical setting may improve overall outcomes. Despite considerable improvements in antiviral therapies, the investigators of the study stated that retention in HIV is still a barrier to bringing an end to the HIV epidemic.
Assessing Outcomes of Patients With and Without HIV Hospitalized With COVID-19 in England
Researchers aimed to assess the clinical outcomes of patients with and without HIV who were hospitalized with COVID-19 during the beginning stages of the pandemic.
Link Between Smoking, Alcohol, and Drug Use and Virological Outcomes in Those Living With HIV
In a 2022 study, investigators aimed to report associations between people living with HIV and the growing evidence suggesting that those with HIV have considerable morbidity from alcohol, cigarette smoking, and recreational drug use.
COVID-19 Outcomes for Those With HIV
Although initial studies showed that there was not a greater risk in mortality in individuals with HIV infected with COVID-19, larger analyses that were adjusted for age showed otherwise.
The HIV Life Cycle
Antiretroviral therapy used to treat HIV have different drug classes that deal with the various stages of the HIV life cycle. The stages of the HIV life cycle are outlined below.